LOCUS       NC_015434              26132 bp    DNA     linear   CON 27-APR-2023
DEFINITION  Micromonospora maris AB-18-032, complete sequence.
ACCESSION   NC_015434
VERSION     NC_015434.1
KEYWORDS    .
SOURCE      Micromonospora maris AB-18-032
  ORGANISM  Micromonospora maris AB-18-032
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP002638.1.
            Genome was manually curated based on annotation generated by the
            NCBI Prokaryotic Genomes Automatic Annotation Pipeline Group.
            Information about the Pipeline can be found here:
            http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html.
            Bacteria available from James E.M. Stach (School of Biology Ridley
            Building University of Newcastle, E-mail: jem.stach@ncl.ac.uk).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2023-06-16 18:53:18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2888432
            Orig. end    :: 2914564
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..26132
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:16132]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16132
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..26132
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..26132
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="8"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     gene            935..2086
                     /locus_tag="VAB18032_RS12975"
                     /old_locus_tag="VAB18032_17710"
     CDS             935..2086
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019032076.1"
                     /locus_tag="VAB18032_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17710"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_081476097.1"
                     /transl_table=11
                     /translation="MGERIRARRELRGWSIRHAASRAGISHTTWSRIERGVQRTDRYMV
                     VDLAAALECSVFDLTGQPYTPADRQLDGARIDAERVWRAMMAHPFDGPPVVGAATVEQV
                     DRESSLVRDLYGRCDYAGALRRLVDLLPALHGVTDQRAAYRLMVPVYGVAMGSLLNVGY
                     SAHAWLAAERCAEAAHLLDDPVAVGVAAANRARVSAYTGAYGPARAYCDRAGADLEGSG
                     ADTALDVLGFLHLARAHHLAGMKDQTTAEEHLDEAARIAAHTGETTSWDLLWGPSNVAL
                     WRMAYLLDTGRPQEALQAAAGVVVGELPAVRQVYYWLDMSRAMVAAERERDAVRMLLAA
                     ERVGPQHTRSSTAAREVARGLLRRGLVSTELRGLCERMGVSAQ"
     gene            2911..3144
                     /locus_tag="VAB18032_RS12985"
                     /old_locus_tag="VAB18032_17720"
     CDS             2911..3144
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787084.1"
                     /locus_tag="VAB18032_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17720"
                     /product="hypothetical protein"
                     /protein_id="WP_013733301.1"
                     /transl_table=11
                     /translation="MTTHGPVMPIWSCGGCDLPWPCPTRRRELRAEYAGAPVSLALYLG
                     VCLVQAAEDMPWAPAGALHRRFIGWARQVPEM"
     gene            complement(3226..3684)
                     /locus_tag="VAB18032_RS12990"
                     /old_locus_tag="VAB18032_17725"
     CDS             complement(3226..3684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020524908.1"
                     /locus_tag="VAB18032_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17725"
                     /product="SUKH-3 domain-containing protein"
                     /protein_id="WP_013733302.1"
                     /transl_table=11
                     /translation="MQRPVSFYRRTRDILKQVGWSAGRAVDTAQWEADLEADGFLPLHP
                     VARRFLTEFGGLTVHNSEPGVTRAREPFTLVPTECSGEADRFIGWGERISRDIAPIGEL
                     AGGTCGCALLGIDEQEEIYLVTDGLATFGRLPRAMDHLALGYMPRKIG"
     gene            complement(3914..4990)
                     /locus_tag="VAB18032_RS12995"
                     /old_locus_tag="VAB18032_17730"
     CDS             complement(3914..4990)
                     /NRPS_PKS="Domain: PKS_ER (17-286). E-value: 1.4e-18.
                     Score: 58.9. Matches aSDomain:
                     nrpspksdomains_VAB18032_RS12995_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 309.4; E-value:
                     4.4e-94)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458237.1"
                     /locus_tag="VAB18032_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17730"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_013733303.1"
                     /sec_met_domain="ADH_N (E-value: 5.7e-27, bitscore: 92.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.3e-27, bitscore:
                     92.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLVARAAGTPPRVEQVDLPDIDTGQVRVTIRAAGVCHSDLSMV
                     DGTIAAPYPLLLGHEAAGVVVEIGDGVDRVAVGDHVVLNWAPPCRACWSCTHGEPWLCE
                     HTGTPATEAGHTLDGEPLHVTLGLGALAEQVVVPQQAMVVVPTDLPFPTAALLGCAVLT
                     GVGAIRRTAAVRPGDSVAVIGLGGVGLSAVAAARAAGAATVIAVDVSPAKADLAHAAGA
                     TDFLLADDTLSRAVRTLTGGRGVDHAVECVGRAATIRTAWRATRRGGQVIVVGMGGKDD
                     IVGLSALEIFHSARTLRSSVYGSSDPDRDLPELARSVLDGSFDLDFLVSDRITLDEAPE
                     ALARMARGEGARTVVQFD"
     aSDomain        complement(4133..4939)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VAB18032_RS12995_PKS_ER.1"
                     /evalue="1.40E-18"
                     /label="VAB18032_RS12995_PKS_ER.1"
                     /locus_tag="VAB18032_RS12995"
                     /protein_end="286"
                     /protein_start="17"
                     /score="58.9"
                     /tool="antismash"
                     /translation="VDLPDIDTGQVRVTIRAAGVCHSDLSMVDGTIAAPYPLLLGHEAA
                     GVVVEIGDGVDRVAVGDHVVLNWAPPCRACWSCTHGEPWLCEHTGTPATEAGHTLDGEP
                     LHVTLGLGALAEQVVVPQQAMVVVPTDLPFPTAALLGCAVLTGVGAIRRTAAVRPGDSV
                     AVIGLGGVGLSAVAAARAAGAATVIAVDVSPAKADLAHAAGATDFLLADDTLSRAVRTL
                     TGGRGVDHAVECVGRAATIRTAWRATRRGGQVIVVGMGGKDDIVGLS"
     CDS_motif       complement(4784..4822)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VAB18032_RS12995_0001"
                     /evalue="2.70E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="VAB18032_RS12995"
                     /protein_end="69"
                     /protein_start="56"
                     /score="10.7"
                     /tool="antismash"
                     /translation="LGHEAAGVVVEIG"
     gene            complement(4987..6405)
                     /locus_tag="VAB18032_RS13000"
                     /old_locus_tag="VAB18032_17735"
     CDS             complement(4987..6405)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 488.3; E-value:
                     3e-148)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014447497.1"
                     /locus_tag="VAB18032_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17735"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_013733304.1"
                     /sec_met_domain="Aldedh (E-value: 1.5e-162, bitscore:
                     539.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESVRTDFYLDGAWVPADGRQSLEVHNTSTEQVIGTVPAGTADDV
                     DRAVAAARAAFEGWAATDPVDRAAHLDRLHAELTARAGDIAHTVATELGTPLKVATRVQ
                     VGLPLTVLRSYVDLAAQPPAPQTVGNSLVVREPVGVIGAITPWNYPLHQIVAKLAPALA
                     AGCTLVLKPSELTPLTAYLLFDAIDAASLPPGVVNLVTGTGPIVGEALAGHPDVDLVSF
                     TGSTATGRRIAHLAADRIARVALELGGKSANVILDDADLTAAVKVGVGNAMLNSGQTCT
                     AWTRMLVHRDRYDEALDLAATAVAGYRLGDPFDPATRLGPLVSAAQRDRVREHIARGLA
                     DGGRLVVGGPDAPVPSRGWFVAPTIIADVDPDSALAQEEVFGPVLAVIPVDDDDHAVRV
                     ANNSRYGLAGAVWSTDEERAVQVARRLRTGAVDINGAPFNPLAPFGGYKQSGLGRELGT
                     HGLAEFCELKAIQR"
     gene            complement(6448..7113)
                     /locus_tag="VAB18032_RS13005"
                     /old_locus_tag="VAB18032_17740"
     CDS             complement(6448..7113)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239:TetR family
                     transcriptional regulator (Score: 153.9; E-value: 9.5e-47)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458235.1"
                     /locus_tag="VAB18032_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17740"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_013733305.1"
                     /transl_table=11
                     /translation="MPRPRQALLSRERIVETAAALIDADGLDAFSTRRLAAALGVRGPS
                     LYNHFATKDEILDAVADSITGQVDVSFFGEVDWREALRRWGHGFRAALAAHPNIVPHLA
                     QGPGRRPAALAMADAVYGGLVAAGWSPARATHIGALMRYFVTGSALGSFARGFVEDPGL
                     YAEQYPHLSQAHRLAEHQQRVDEGAFALGLEALIDGLSHTYERLVGPLAPLPPEGGTH"
     gene            7203..8351
                     /locus_tag="VAB18032_RS13010"
                     /old_locus_tag="VAB18032_17745"
     CDS             7203..8351
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 438.2; E-value:
                     4.1e-133)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461364.1"
                     /locus_tag="VAB18032_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17745"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_013733306.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-33, bitscore:
                     114.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-29, bitscore:
                     101.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.6e-51, bitscore:
                     172.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHLSAEQVAVRELAADFVNREVVPHAATWDRREAVDPGIVGKL
                     GDVGFLGLTIDEEYGGSGGDHLAYCLVLEELGRGDSAVRGIVSVSLGLVAKSIATHGTR
                     EQREQWLPALCSGTALGCFALTEPDSGSDAAALTTRAVRDGDDWLLTGRKTFITNGTTA
                     DVALLFARTGGPGHRGITAFLVPTDSPGLSRSEIKGKLGLRGQATAELVLDGVRVPDTA
                     RLGECGAGFRLALGTLAKGRMSVAAGCVGIAQGCLNAAVDYAGARTQFGKPIAGHQLVQ
                     QLLARIAVDTAAARLLVWQVADLIDRGQPYATEASMAKLFASEAAVRAANDAIQVFGGY
                     GYIDEYPVGKYLRDARVTTLYEGTSQIQQLLIGRALTGVNAF"
     gene            8371..9543
                     /locus_tag="VAB18032_RS13015"
                     /old_locus_tag="VAB18032_17750"
     CDS             8371..9543
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 326.6; E-value:
                     3.6e-99)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442827.1"
                     /locus_tag="VAB18032_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17750"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_013733307.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-18, bitscore:
                     65.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.3e-20, bitscore:
                     71.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-46, bitscore:
                     157.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFGLSDEERAIRDTARDFITREVMPLEQELLRRERAHQPGLEPS
                     ELRELQLKAKKFGFWGLATPQEYGGMDLPAVMQSLIWTEIGRTFVPFRFGGEADNILFY
                     ATEEQRQEFLLPTIAGDRNSCFAITEPGAGSDAANIRFRARRDGDDWILNGEKTFITGG
                     NEADFAIVIAVTDPERGARNGGATAFLVDRSMGWRSEFIPTMGEGGPASLFFDDVRVPH
                     RNILGEEGQGFALAMQWIGKGRYTIPSHAVGIAERALRMAIDHANTRETFGTKIGTNQA
                     IQWMIADSETELEAARWLILRAAWTVDAGMDPRHASSMAKLYGAGMVNRVVDRVMQIHG
                     GMGYTRELPIERWYRQVRLYRIFEGTDEMQRLIISRDLLRGYTKLGGHLG"
     gene            9540..10004
                     /locus_tag="VAB18032_RS13020"
                     /old_locus_tag="VAB18032_17755"
     CDS             9540..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461362.1"
                     /locus_tag="VAB18032_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17755"
                     /product="MaoC family dehydratase"
                     /protein_id="WP_013733308.1"
                     /transl_table=11
                     /translation="MRTFASIDELAGAVGEPLGPGPWFPVDKRRVELFADATDDHQWIH
                     LDQERAAAGPYGGTIAHGYLTLSLIPALVGQLYRVDGVRMGINYGLNRVRFPAPVRVGS
                     AVRVVATIDQVTPFDGGAQLVATVTVHNDGGDKPVCVAETVSRLYTDPPR"
     gene            10001..10894
                     /locus_tag="VAB18032_RS13025"
                     /old_locus_tag="VAB18032_17760"
     CDS             10001..10894
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 58;
                     E-value: 9.9e-18)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.2"
                     /locus_tag="VAB18032_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17760"
                     /product="AMP-binding protein"
                     /protein_id="WP_013733309.1"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-13, bitscore:
                     47.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLSPATVLAGSARRHADTVAVVDGRVRVTYAELWWEARCYGAG
                     LRAAGVRAGDTVALLAPNVVDFPRVYYAALAAGAHAVPIGAPTSPQTVHLLRGARLLVC
                     HTSQLAAGQWVSARAGVPLVTVGPTRGPSGVPRLEDLSDPAPGGAAADPDTDDDPAGRT
                     ATDPDDGDVVLSCLPLGGRFGQDVALTGTFAAGATLVLLSRFTGPAALELMLREEVTVF
                     HGTSAMYAALLDAARGRQTLPRLRRCVSRTPLPPALGQPFTTAFATVVTVAEEKSRYGG
                     GRRQRWRCRHRQGKGR"
     gene            complement(10903..12540)
                     /locus_tag="VAB18032_RS13030"
                     /old_locus_tag="VAB18032_17765"
     CDS             complement(10903..12540)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136.5; E-value:
                     1.9e-41)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786850.1"
                     /locus_tag="VAB18032_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17765"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_013733310.1"
                     /transl_table=11
                     /translation="MSDSFVVCSNLSFSWPDDTPVFQDLSFTIGAGRTGLVAPNGAGKS
                     TLLRLLAGEYRPTAGSVSTQGVLGYLPQTLPLVGDRTVAEVLEIAPLIGALHAIESGDA
                     DEEHFTTIGNDWDIEERTRAQLDRLGLGDLAFDRRLDTLSGGQVVSLGLAAQLLKRPDV
                     LLLDEPTNNLDIEARHKLAEVLEQWTGCLLLVSHDRALLDRMDRIAELDRGDLRFYGGN
                     FTAYEAAVRAAQEVAEKNVRNAEQELKREKRELQEARERAARRAGNASRNLKNAGLPKI
                     FAGTLKRNAQESAGRADELHSARVSEAKARLDEAGQALRNEQKLSLELPGTQVPAGRTL
                     LAAERMQVRYGGRPVFADDGVDLTIRGPERIALLGANGAGKSTLLRLVTGTLEPEGGQI
                     RRADGRIAYLSQRLDLLDPERTVAENLAVFAPQAPEARRMHLLARFLFRGARAQLPVGV
                     LSGGERLRATLACVLGAEPAPQLLLLDEPTNNLDLVSVGQLESALNAYRGALLVVSHDE
                     RFLAEIKVSRWLRLAEGRLLETGPPPAD"
     gene            complement(13031..13858)
                     /locus_tag="VAB18032_RS13035"
                     /old_locus_tag="VAB18032_17770"
     CDS             complement(13031..13858)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292:hypothetical
                     protein (Score: 317.3; E-value: 1.1e-96)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786739.1"
                     /locus_tag="VAB18032_RS13035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17770"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_013733311.1"
                     /transl_table=11
                     /translation="MTRDKAAPPGIDTSIPSVARVYDFFLGGKDNFEVDRKVAEHALRI
                     TPDGPAAGQANRAFLRRVIRFLVTEAGIDQFLDIGSGLPTQGNVHEVATEHNPKARVVY
                     VDNDPIVLAHGRALLAEEGTATVIQADVRAPQEILNNPEVRRFLDFDRPIGLLLFAILH
                     HVGDDEQPRALAAELIDALPSGSYVAISHFRDPGERDPEGSRKAREVERVFNESLGTGR
                     WRTDEEILAFADGLTVLEPGLVPLAEWRPESGTPTPQQTDTYHTFVGLLARKP"
     gene            complement(13987..14403)
                     /locus_tag="VAB18032_RS13040"
                     /old_locus_tag="VAB18032_17775"
     CDS             complement(13987..14403)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735467.1"
                     /locus_tag="VAB18032_RS13040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17775"
                     /product="RidA family protein"
                     /protein_id="WP_013733312.1"
                     /transl_table=11
                     /translation="MSGARVVAGKAVPRGRFPHVKVAGGFAFVSGTSSRRPDNTIAGAT
                     VDALGTTSLDIEVQTRAVIENMRDILREVGADLSDLVQVTTYLVSMNDFGGYNRVYAEL
                     FDETGPTRTTVAVHQLPHPHLLIEMQGIALLPVD"
     gene            complement(14400..15113)
                     /locus_tag="VAB18032_RS13045"
                     /old_locus_tag="VAB18032_17780"
     CDS             complement(14400..15113)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072556.1"
                     /locus_tag="VAB18032_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17780"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_013733313.1"
                     /transl_table=11
                     /translation="MIDTIAARLDEAAVTRTALAQFGADAGLDVATAYQVQDALVARRV
                     GRGEAVVGVKLGLTSRAKMTQMGVDEVIWGRLTDAMHICDGGTVDLSGHIHPKVEPEVA
                     FLVEGGAIAAVAPAVELIDSRYRDFRFTLAEVIADNTSASGFVVGPWQPVPDNVDNLGV
                     LLEVDGRVAQVGSTAAILGDPRRALPEAARLAGELRDGWVLLAGAATAAVPLTPGAHVR
                     VTVEQLGTVSLRASA"
     gene            complement(15110..16132)
                     /gene="dmpG"
                     /locus_tag="VAB18032_RS13050"
                     /old_locus_tag="VAB18032_17785"
     CDS             complement(15110..16132)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 192.6;
                     E-value: 2.1e-58)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786913.1"
                     /locus_tag="VAB18032_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17785"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_013733314.1"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-61, bitscore:
                     206.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLYIQDVTLRDGMHAIGHRYTVDQVRTIAAALDAAGVAAIEVA
                     HGDGLAGSSVNYGHGAASDAEWIAAAAEVMTNAKLTTLLLPGIGTIADLKAAKALGVTS
                     VRIATHCTEADISAQHISWARDNGMDVSGFLMMSHMFDPAGLAAQAKLMESYGAHCVYV
                     TDSGGRLTMADVAQRADAYRQVLDPTTEIGIHAHHNLSLGVANSLVAVEHGVRRVDASL
                     AGMGAGAGNAPLEVFVAVAELNGWKHGCDVFALMDAAEDLVRPLQDRPVRVDRETLSLG
                     FAGVYSSFLRHAESAAGRYGVDVRTILLELGRRKMVGGQEDMIVDVALDLVRDAGKDPQ
                     "
     gene            complement(16129..17040)
                     /locus_tag="VAB18032_RS13055"
                     /old_locus_tag="VAB18032_17790"
     CDS             complement(16129..17040)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018812229.1"
                     /locus_tag="VAB18032_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17790"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_013733315.1"
                     /transl_table=11
                     /translation="MSTGVAVIGSGNIGTDLMIKVLRLSESLRMVAMVGIDPDSDGLAR
                     ARRLGVATTAAGVDGLVAMPEFADVGIVFDATSAGAHRHNDAVLRAHGRRVVDLTPAAI
                     GPYVVPPVNLDAHLGERNVNMVTCGGQATVPIVAAVRRVTPVAYGEIVASISSRSAGPG
                     TRANIDEFTETTARAIEVVGGAGRGKAVIVLNPAEPPLLMRDTVYCLCPDPDADRDAIA
                     ASVEAMVAAVQQYVPGYRLKQQVQFTEVDTYVPALGGHFVGIQVSVFLEVSGAGHYLPA
                     YAGNLDIMTSAALRTAERMVSS"
     gene            complement(17159..17953)
                     /locus_tag="VAB18032_RS13060"
                     /old_locus_tag="VAB18032_17795"
     CDS             complement(17159..17953)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786915.1"
                     /locus_tag="VAB18032_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17795"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_013733316.1"
                     /transl_table=11
                     /translation="MSADIKGAAAALRQAYASGVACEPLRDDLLPAGDLTAAYAVQQAQ
                     VSDWLAEGRRLVGAKVGLTSRAVQEAFGVFQPDFGVLFADMAVPDGAEIDPRTLLQPRV
                     EAEVAFVLGRDLPYDQVTVADVVRATDHLLPAIEIVDSRIANWDISIVDTVADNASSGR
                     YVLGTSPRRLGEVDLRLCGAVLEQGGEPVSVGAGAACLGNPLHAVAWLAGTLAANGRPL
                     RAGDTVLSGALGPMVAVTPGAAYEARISGLGSVRACFSKGGS"
     gene            complement(17950..19467)
                     /locus_tag="VAB18032_RS13065"
                     /old_locus_tag="VAB18032_17800"
     CDS             complement(17950..19467)
                     /EC_number="1.2.1.85"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 470.7; E-value:
                     6.5e-143)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007464170.1"
                     /locus_tag="VAB18032_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17800"
                     /product="2-hydroxymuconic semialdehyde dehydrogenase"
                     /protein_id="WP_013733317.1"
                     /sec_met_domain="Aldedh (E-value: 2.2e-159, bitscore:
                     529.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGRTTRWPSGLIDGRRSGDLLLPNYVGGEFVTGGTSFAKVSPV
                     TGETLLHVAEADQATVDAAVTAARAALRGPWGAMGEGERAAVLRRVADELERRFDDLVA
                     AEVADTGKSVAQARTLDIPRGAANFRTFADIITATPTESFTTVTASGGRALNYAVRKPV
                     GVVAIIVPWNLPLLLLTWKVAPALACGNAVVVKPSEETPSSATVLAEVMAAAGVPDGVF
                     NLVHGFGPGSAGEALTRHPGVDAITFTGESATGSAIMRAAADGVKAVSFELGGKNAGLV
                     FADADLDAAVEGSVRSSFTNGGQVCLCTERIYVQRPVFEEFAARLAKRAEELAFGWPSE
                     PATMTMPLISAKHREKVLGHYELARAEGATVLAGGGVPVFGDDRDSGSYVQPTVLTGLG
                     RHARTMREEIFGPVCHIAPFDDEDEAFALANDSEYGLAATVWTRDVGRAHRAGARLDAG
                     LVWVNTWFLRDLRTPFGGVKASGVGREGGTHSLHFYSELTNVCVDLG"
     gene            complement(19480..19728)
                     /locus_tag="VAB18032_RS13070"
                     /old_locus_tag="VAB18032_17805"
     CDS             complement(19480..19728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783795.1"
                     /locus_tag="VAB18032_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17805"
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="WP_013733318.1"
                     /transl_table=11
                     /translation="MILGEVVAKVWPDKILPTLQGRRLVLVRPRSEGPDLVAIDPLNVG
                     VGTVVLIATDEAAAAATGEPTADAAVVALVADSTTER"
     gene            complement(19728..20054)
                     /locus_tag="VAB18032_RS13075"
                     /old_locus_tag="VAB18032_17810"
     CDS             complement(19728..20054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783794.1"
                     /locus_tag="VAB18032_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17810"
                     /product="BMC domain-containing protein"
                     /protein_id="WP_013733319.1"
                     /transl_table=11
                     /translation="MPSDIAIGIVETRGVVALSAGIEAMIKTADVRCIAVERVTSGYLA
                     AAVQGTLAAVRQAVAAGEAAIRQHGELRSSQVYPKPHPTTAALLEDPEAARIREVMASL
                     RGDG"
     gene            complement(20075..20365)
                     /locus_tag="VAB18032_RS13080"
                     /old_locus_tag="VAB18032_17815"
     CDS             complement(20075..20365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783793.1"
                     /locus_tag="VAB18032_RS13080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17815"
                     /product="BMC domain-containing protein"
                     /protein_id="WP_013733320.1"
                     /transl_table=11
                     /translation="MRNMAAGFVEAEGYTAIFDAVDAMVKATEVEVTRVVRLGGGIVAV
                     ALRGDLATVEEAVDIGEETAKAKSRKVRSIVFASPCDAVSALAVDPRLVGN"
     gene            complement(20386..21213)
                     /locus_tag="VAB18032_RS13085"
                     /old_locus_tag="VAB18032_17820"
     CDS             complement(20386..21213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783792.1"
                     /locus_tag="VAB18032_RS13085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17820"
                     /product="2-amino-5-chlorophenol 1,6-dioxygenase subunit
                     alpha"
                     /protein_id="WP_013733321.1"
                     /transl_table=11
                     /translation="MADTGIVAGALLPGMPHLLAEKPAQCWADLAAAAREVGDRLRRLK
                     PDVVLLLSTQWFTVLGHQFQCDPNPRGEHVDENWYAYDYGELRYDLRFDVPFTERWTDH
                     VNKAGMQARRTRYDGFPIDTGTIVTSALLDPDRELRWAQVSCNLYADAQTLADVGAAGA
                     AAAREAGVRAAVVVVTGMSSGLIQQWIEPHDDHVSDPGHDRWNRRVLDLLTAGKVDEVL
                     KIREDFARQAQADSQFRALAFAAGAGATAGPAQLHAYGPLWGTGGAVLSWNLP"
     gene            complement(21206..22195)
                     /locus_tag="VAB18032_RS13090"
                     /old_locus_tag="VAB18032_17825"
     CDS             complement(21206..22195)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783791.1"
                     /locus_tag="VAB18032_RS13090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17825"
                     /product="tRNA U-34 5-methylaminomethyl-2-thiouridine
                     biosynthesis protein"
                     /protein_id="WP_013733322.1"
                     /transl_table=11
                     /translation="MSRVFRVPVAPARSGGARRYDTTERPSAEPTPARAGIVAGVLSPH
                     PPHLIYAENPPQNEPRSTGGWEVLRWAYERLRKRIREVHRPDVLIVHAPHWITMVGHHV
                     NCVPNPRGVSVEPIFPHLFRYSYDFRTDVELGEAIADEATDLGLVTRKLHDPRVRVDYA
                     TIGALHLVNPAWDIPVVSLSANNNPYFYSEASLEEMEVLGEATRRAVERTGRRAVLLAS
                     NSLSHLHWHEEPELPEDMEREHPYNNHQYRWDMKLLEAIRRGPTAPLRELITEHIEATA
                     SETKAGSLTWMLAAMGWPQVPGDVMGYGTIIGTGNAVVEWTPEGGHRG"
     gene            complement(22192..24231)
                     /locus_tag="VAB18032_RS13095"
                     /old_locus_tag="VAB18032_17830"
     CDS             complement(22192..24231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783790.1"
                     /locus_tag="VAB18032_RS13095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17830"
                     /product="hydantoinase B/oxoprolinase family protein"
                     /protein_id="WP_013733323.1"
                     /transl_table=11
                     /translation="MTKTLNPIDLEIVTEGLISIVREMRQTIFRTAHSPVIADAQDFSC
                     ALFDPQGQMVAQGRDMPGHVIAMPASVAEIFADFADEMRPGDLYIVNDPYRGGSHLNDV
                     TLITPVFVDGELFLFPCVRMHWADIGGMTPGSVSGQATEILQEGLRIPPIKLIEQGRPN
                     AAAYAILFANVRMADERRGDLESCIAACFTAERRLRELVGRYGAPLLLDSVAANMDRTE
                     QRLRDRIRQLPDGVYRYEDYLDLYTDGRYDPALVRCVLTIDGDEIDADFRGSSTQVAAV
                     VNSSRAMTVAGVFIAVKSALDPGGLVNHGAFRPLRVHTEPGTVVHVAYPAPANAHSEVR
                     KRVISAVMATLSQVAPDLIAADQFGTTFQNLIGGVDQRTGRSYLYYDYPAGGNGGFLES
                     DGPSAMNPVDLGDISTIQSVERLETEIPIVVDASELRLGSCGDGARRGGLGSRRETRLL
                     ASNGAYSVQTDRTTVPPYGLHRGGPGAPTVTFVRRADGERVDFDTPGKVAGFAMRSGDV
                     LVMESAGGGGWGDPLEREPAAVADDVTQGYLDADDAQHRYGLRFDADGRVDAAATAAAR
                     QELRRRRTWLRVGTTDRQPYTGERGRRRLAYVGPGTGLADGALVEIHGPHPAPLRAWVR
                     HDPDLTDDQLALDDDGLQILGAEPDERTFVRVLADRGTTGEGPA"
     gene            24374..25201
                     /locus_tag="VAB18032_RS13100"
                     /old_locus_tag="VAB18032_17835"
     CDS             24374..25201
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195:IclR family
                     transcriptional regulator (Score: 246.2; E-value: 4.7e-75)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783789.1"
                     /locus_tag="VAB18032_RS13100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="VAB18032_17835"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_013733324.1"
                     /transl_table=11
                     /translation="MSQVAGPSPAAEGPAARESGTQALDRALSVLLAFRSGGVERKVSD
                     VSRELGLHKSTASRLFRALADTGFLQRNEETGAYRLGVTVFELGACFLEGLDMHALARP
                     LLHQLAQDEGESVNLSIRDELDALSIYIERGTRNVQLVSRLGRRIPLWCSAAGKALLLD
                     LDDEQIRAMFADTQFTPLTPNTITDLDTFAKRMHQVREQGWALNDEESEEGLRVVAAPV
                     RDRLGQVTAAISISGPIFRLDETRVAELAAAAVRTANELSRQLGHGVGAVWGD"
ORIGIN
        1 gtcggcagga gaagaaaatt ttgaagatct ctcctccgtg cgtactgccg ccaacgatgg
       61 aggtccagcc agtccttcga actcctcggt tccagagcag cgtgccgacg aggggactag
      121 cagtaagaag catctcgacg ccttgacgct tcaagtggag gcggaggagt tagttcttag
      181 aaatatccga tctttttacc gagggcatct cgatatagtc cgggatgtcc gaatcaatgg
      241 cgtgcgtgcc gatgcgctag tggtgtcaca gtcgtcgaat atgccgaact tgattcttga
      301 cattcggatc gtattggttc accctaattg gctttattac tttcgtcgca ggctgcagga
      361 aagcattcgc tggatctctc aagtgaaggg cgaggctgtc gctgaactgc atgccgatgt
      421 taagcctgtt gtgctatttg tgttcaatca aaatccctcc gaggcgaccg tgctgtcagt
      481 ccggagattg atttctcgcc tactggacga ctacttggca gccaggagca ggtcgctcca
      541 cggcttgatt ttcttaacca ccgttgctga tttgcgaaag acggataccc tggcggctga
      601 cttgattgcg cagggcgggc ttgcgatgga caccctcagt ccccggtcag atcgaagtga
      661 gcccatcggt ggatgatcgc gcgtgacccc agcagggcga agactcagcg gtgcgtgcga
      721 tctcagtcca gcagatcagg tgagtttgag gggcgtgacg acgtgccggt cgaagcgcga
      781 tgagggtcag gcggccgccc ctgcgaagca ctgtctgtca ggagtaccgt cggtggcagc
      841 gtggttgccg gttgtcgtgc tggctgcgtg ccgtatctga tcgttgttcg agaggatcac
      901 tgtgcctcgc cgacctatac ctgctgaccc ttcggtgggt gagcgcatcc gggcccggcg
      961 cgagttgcgt ggctggagta tccggcatgc cgcgagtcgc gcgggtatct cgcataccac
     1021 gtggtcacgg atcgagcgcg gtgttcagcg tacggatcgg tacatggtgg tggatctggc
     1081 cgcggccctg gagtgttcgg tgttcgacct tacggggcag ccgtatacgc cggctgatcg
     1141 gcagcttgat ggtgcgcgta tcgacgccga gcgggtgtgg cgggcgatga tggcgcatcc
     1201 gttcgatggg ccaccggtcg tcggggcagc cactgtggag caggtggatc gggagtcgtc
     1261 gctggtgcgc gatctgtacg gccggtgcga ctacgccgga gccctgcgcc ggctggtgga
     1321 cctccttccg gcactgcatg gtgtgactga tcagcgggcg gcgtaccggt tgatggtgcc
     1381 ggtgtacggg gtggcgatgg gttcgttgct gaacgtgggt tactcggccc atgcctggtt
     1441 ggcggcggag cgttgtgcgg aggctgcgca cctgcttgat gacccggttg cggtgggggt
     1501 ggcggcggcg aatcgggctc gggtgtcggc gtacaccggc gcgtacggcc cggcgcgggc
     1561 gtactgcgat cgggccggag cggacctgga gggcagcggt gcggacaccg cgctggatgt
     1621 gctcgggttc ctgcacctgg ctcgcgcgca tcacctcgcc ggaatgaagg atcagaccac
     1681 ggccgaggag cacctcgatg aggcggcgcg gatcgccgcg cacaccgggg agacgacgag
     1741 ctgggacctg ttgtgggggc cgagcaacgt ggcgttgtgg cggatggcct acctgctcga
     1801 caccggacgt ccgcaggagg cgttgcaggc ggctgccggg gtggtggtcg gggaactgcc
     1861 ggcggtgcgg caggtgtact actggctgga catgagccgc gcgatggtgg cggctgaacg
     1921 ggagcgagac gcggtgcgga tgctgctggc ggccgaacgg gtcggcccgc agcacacccg
     1981 gtcatcgacg gcggcgcgag aagtcgcacg tgggctgctg cgtcgagggc tggtctctac
     2041 ggaactgcgg ggcctgtgcg agcgcatggg ggtctccgcc cagtagtggt gcgtaggtgt
     2101 tccatcaccc accgtgccgt ccataacgtt ccgatcagga cacgacggca ggaagcaccc
     2161 gctacgccga ctctgtccgc cgggtggcga cgccaacccg agcgcgacac ctgacagccg
     2221 cgctgccgtc gccacccgcc gacccatgac aagggaggcg gaacctgtgg caatccggtc
     2281 cgagctgcgc gacattctgc ggtggctgct gcgacgcgca gacttacccc cgccgcccgg
     2341 aacgggccaa cgccaccagg ccgccgagca ggccgcagcg cagcggaggc tgctggacca
     2401 ggcgaagagg tcacgggaca cgcactggca ccgcgaaccg atccagacca cgccgtacgc
     2461 gccgacgacg cgtgatcagc gcaccgggga cgcgacacgg agccaccggt gagcccagcg
     2521 cgggcaggtt ctcctgcgat gccgccccag gccaccggag agtctcgtac gacgagtacc
     2581 tgtcggctac cgcgttgacc tttgcccggc ggcatcggcc ggtgtggtgt tggcggcggt
     2641 ggcggcgggt ctgtcggtgc ggagctgacc tgccctgccg tgctcgacat cgcattccga
     2701 tcaatcgtgg tcactggcct ggggagggtg agcagtgacc ggcgggccgg aacagacgat
     2761 cctcgccgta cacgttcgtg ggcttgatgg gatgtgtgtg ggttgtcggg tgtggtgggc
     2821 gcggttggtg ccgtacccgt gttggcaggt ggagtgggcg acgagccggc aggctcgcgc
     2881 gagcgtggcc cggtttctgg gcggtgcgcg gtgaccaccc atggcccggt gatgccgatc
     2941 tggagttgtg gtggctgtga cctgccctgg ccgtgtccga cgcggcggcg ggagttgcgc
     3001 gcggagtacg cgggcgcgcc ggtgtcgctg gctctctatc tcggtgtctg tctcgtgcag
     3061 gccgccgagg acatgccgtg ggcaccggcc ggggcgctgc atcgccggtt catcggctgg
     3121 gccaggcagg tgccggaaat gtaggagcga gtcctcgtgc ctaccgtgag cccggtcagc
     3181 gagcgcggtt ctgagcggat agttcggtcg gggagaggag cagcgctagc cgatcttgcg
     3241 aggcatgtat ccgagagcaa ggtggtccat ggccctcggc agacggccga aggtggcgag
     3301 cccatcggtg acgaggtata tctcttcctg ctcgtcgatg ccgagcagcg cgcatccgca
     3361 ggttccaccc gccagttcac cgatcggcgc tatgtcacgg ctgattcgtt ctccccatcc
     3421 aatgaatcga tcagcttcgc cggagcattc ggttggaacc agcgtgaagg gttcccgagc
     3481 acgggtgaca ccaggctcgc tgttgtggac ggtgagcccg ccgaactcgg tgaggaaccg
     3541 tcgcgcgacc ggatgcaggg gaaggaagcc gtctgcctct aggtcagcct cccactgtgc
     3601 tgtgtccaca gcccgaccgg cggaccagcc cacctgtttc aggatgtcgc gcgttcggcg
     3661 gtagaagctg actgggcgct gcatggcagc gactgtaggc gacgaacgta cgacacggtg
     3721 gtctggatac accgagcggt gtggacctga cggagcggaa gggccggcac cggctggctg
     3781 ggccgccatc cctcgctccg cgccgtgcgg atgactgccg cgaccatcga tggacgaaca
     3841 gggaccggcg ggccgccgat ccagagccct tcctggtcaa cgccacgtcg atcccctcgc
     3901 cgccggatgc gcgtcagtcg aactgaacca ccgtacgggc gccctcgcca cgggccatcc
     3961 gggccagagc ctcaggtgcc tcgtcgaggg tgatccggtc gctgaccagg aagtcgaggt
     4021 cgaagctgcc gtcgagcacc gagcgggcca gctccggcag gtcccggtcc gggtcggagg
     4081 agccgtacac cgaggagcgc agggtccggg cggagtggaa gatctccagt gcgctgagac
     4141 cgacgatgtc gtccttgccg cccatgccga ccacgatgac ctgtccgccg cgacgggtgg
     4201 cccgccaggc ggtgcggatg gtggcggccc ggccgacgca ctccaccgca tggtcgacgc
     4261 cgcgaccccc ggtcaacgtt cgtaccgcgc ggctgagggt gtcgtcggcg agtaggaagt
     4321 cggtggcacc ggcggcgtgg gccaggtcgg ctttggcggg ggagacgtcg acggcgatga
     4381 cggtggcggc accggcggcg cgggcggcgg cgaccgcgga caggccgacg ccgccgaggc
     4441 cgatgacggc gaccgagtcg ccggggcgca cggcggcggt acgccggatc gcgccgacgc
     4501 cggtgagcac cgcgcagccg agcagcgccg cagtggggaa gggcaggtcc gtcggtacga
     4561 cgaccatcgc ctgctgcggc accaccacct gctcggccag cgcgccgagg ccgagggtga
     4621 cgtgcagcgg ctcgccgtcg agggtgtgcc cggcctctgt ggctggggtg ccggtgtgtt
     4681 cgcacagcca gggttcgccg tgggtgcagg accagcaggc gcggcagggt ggcgcccagt
     4741 tgagcaccac gtggtcgccg accgcgaccc ggtcgacgcc gtcgccgatc tcgacgacca
     4801 caccggcggc ttcgtggccg agcagcagcg ggtacggggc ggcgatggtg ccgtcgacca
     4861 tggacaggtc ggagtggcag acgccggcgg cccggatcgt cacccgtacc tgcccggtgt
     4921 cgatgtcggg caggtcgacc tgctcgacgc gtgggggagt gccagcggcc ctggcgacga
     4981 ggcccctcac cgctggatcg ccttcagttc gcagaactcc gccagcccgt gggtgcccag
     5041 ttcgcggccg aggccggact gcttgtagcc gccgaacggt gccagggggt tgaagggtgc
     5101 gccgttgata tcgacggccc cggtgcgcag ccggcgggcc acctgcaccg cgcgttcttc
     5161 gtcggtggac cagaccgcgc cggccagccc gtagcgggag ttgttggcga cccgtacggc
     5221 gtggtcgtcg tcgtcgacgg ggatgaccgc caggaccggc ccgaagacct cttcctgggc
     5281 cagggcgctg tcggggtcga cgtcggcgat gatcgtcggg gcgacgaacc agccgcgcga
     5341 cggcacgggg gcgtcgggtc cgccgacgac gagtcggccg ccgtcggcca ggccacgggc
     5401 gatgtgctcg cgtacccggt cgcgttgcgc agcggagacc agggggccga gtcgggtggc
     5461 cgggtcgaac gggtcgccga gccggtagcc ggcgaccgcc gtggcggcca ggtcgagggc
     5521 ttcgtcgtag cggtcgcggt gcacaagcat cctggtccac gcggtgcagg tctgccccga
     5581 gttgagcatc gcgttgccga cgccgacctt gaccgcggcg gtcaggtcgg catcgtcgag
     5641 gatgacgttc gccgacttgc cgccgagttc caacgcgacc cgggcgatcc ggtcggcggc
     5701 caggtgggcg atgcgccggc cggtggcggt ggagccggtg aaggagacca ggtccacgtc
     5761 ggggtggccg gcgagggcct cgccgacgat cggcccggtg ccggtgacca ggttgaccac
     5821 gcccggtggc aggctggcgg cgtcgatggc gtcgaagagc aggtacgcgg taagcggggt
     5881 cagctcgctc ggcttgagca ccagcgtgca cccggccgcc agggcgggag cgagtttggc
     5941 gacgatctgg tgcagcgggt agttccacgg ggtgatcgcc ccgatgacgc cgacgggttc
     6001 gcgtaccaca agggagttgc ccacggtctg cggcgccggc ggctgggcgg ccaggtcgac
     6061 gtagctgcgc aggacggtca gcggaagtcc gacctggacg cgggtggcga ccttgagcgg
     6121 ggtgccgagt tcggtggcga ccgtgtgggc gatgtccccg gcgcgggcgg tcagctcggc
     6181 gtgcagtcgg tcgaggtggg cggcccggtc gacggggtcg gtcgcggccc agccctcgaa
     6241 ggcggcccgg gcggcggcca ccgcccggtc gacgtcgtcg gcggtgccgg ccgggaccgt
     6301 gccgatgacc tgctcggtgc tggtgttgtg cacctccagc gactgccggc cgtcggcggg
     6361 aacccaggct ccgtcgaggt agaaatcggt ccgtacggat tccatgtgcc tccacctcga
     6421 ctaaaactag cggtgcaagt ttggactcta gtgcgtcccg ccctccggcg ggaggggggc
     6481 aagtggacct acgagccgct cgtaggtgtg cgacagcccg tcgatgagcg cctccaggcc
     6541 gagggcgaac gcgccctcgt cgacgcgctg ctggtgctcg gcgaggcggt gggcctggct
     6601 caggtgcggg tactgctcgg catagagccc cggatcctcc acgaagcccc gggcgaagga
     6661 gccgagcgcc gaaccggtca cgaagtagcg catcagcgcg ccgatgtgcg tcgcccgagc
     6721 cggcgaccaa cccgccgcga ccagcccgcc gtagacggcg tcggccatgg ccagcgccgc
     6781 cggacgtcga ccgggaccct gggccaggtg cggcacgatg ttcggatgcg ccgccagggc
     6841 ggcccggaac ccgtgccccc agcgacgcag tgcctcacgc cagtcgacct cgccgaagaa
     6901 cgacacgtcc acctggccgg tgatgctgtc cgcgaccgcg tcgaggatct cgtccttggt
     6961 ggcgaagtgg ttgtacagcg agggcccgcg tacgccgagc gcggcggcga gccgccgggt
     7021 ggagaacgcg tcgagtccgt cggcgtcgat caacgcggcg gcggtctcga cgatccgctc
     7081 ccggctgagc agtgcctgtc gaggccgggg catgggcgtc ctccttcgca tcggtggctc
     7141 gcggggaact gtcgcacacc ggggtctgga cagcataaaa cttgcagcgc tagtttaatc
     7201 gtatggacct tcacctctcc gccgagcagg tcgcggtccg ggagctcgcc gccgacttcg
     7261 tcaaccgcga ggtggtgcca cacgcggcga cctgggaccg gcgcgaggcg gtcgaccccg
     7321 gcatcgtcgg caaactcggc gacgtcggct tcctcggcct caccatcgac gaggagtacg
     7381 gcggctccgg cggcgaccat ctcgcgtact gcctggtgct tgaggaactc ggccgaggcg
     7441 actccgccgt acgcggcatc gtgtcggtct ccctcggcct ggtcgccaag tcgatcgcca
     7501 cccacggcac gcgagagcaa cgcgaacagt ggctgcccgc gctctgctcg ggcaccgcgc
     7561 tcggctgctt cgcactcacc gaaccggaca gcggctcgga cgccgcggcg ctgaccaccc
     7621 gcgcggtccg cgacggcgac gactggctgc tcaccggccg caagacgttc atcaccaatg
     7681 gcaccaccgc cgacgtcgcg ttgctcttcg cccgcaccgg cggccccggc caccggggca
     7741 tcaccgcgtt cctggtgccc accgacagcc cgggcctgtc ccgatccgag atcaagggca
     7801 agctgggcct gcgcggacag gccaccgccg aactcgtcct cgacggcgta cgggtgcccg
     7861 acaccgcccg cctcggcgag tgcggcgccg gcttccggct ggcgttgggc accctcgcca
     7921 agggacgcat gtcggtcgcc gccggatgcg tcggcatcgc ccagggctgc ctgaacgccg
     7981 ccgtcgacta cgccggcgcc cgcacccagt tcggcaaacc catcgccgga caccaactcg
     8041 tgcagcaact gctggcccgc atcgccgtcg acaccgccgc ggcgcggctg ctggtctggc
     8101 aggtcgccga cctgatcgac cggggccagc cgtacgccac cgaggcgtcg atggccaagc
     8161 tgttcgccag cgaggccgcc gtgcgtgccg ccaacgacgc catccaggtc ttcggcgggt
     8221 acggctacat cgacgagtac ccggtcggca aatacctgcg cgacgctcgc gtcaccaccc
     8281 tctacgaggg caccagccag atccagcagc tactcatcgg gcgggcgctc accggcgtca
     8341 acgccttctg acgaaaggaa ccgtgagcac atggacttcg ggctgtccga cgaggaacgg
     8401 gccatccgcg acaccgcccg cgacttcatc acccgcgagg tcatgccgct ggagcaggaa
     8461 ctgctgcgcc gggaacgggc ccaccagccc ggcctggaac cctccgagct gcgcgagttg
     8521 cagctcaagg ccaagaagtt cggcttctgg ggcctggcca cgccgcagga gtacggcggc
     8581 atggacctgc ccgccgtcat gcagtcgctg atctggaccg agatcggccg caccttcgtg
     8641 ccgttccgct tcggtggcga ggccgacaac atcctcttct acgccaccga ggagcagcgg
     8701 caggagttcc tgctgcccac catcgccggt gaccgcaact cctgcttcgc catcaccgag
     8761 ccgggggccg gctcggacgc cgccaacatc cgcttccgcg cccgacgcga cggcgacgac
     8821 tggatcctca acggcgagaa gaccttcatc accggcggca acgaggccga cttcgccatc
     8881 gtcatcgccg tcaccgaccc cgagcggggc gcccgcaacg gcggggcgac cgccttcctg
     8941 gtggaccggt cgatgggctg gcggtcggag ttcatcccca ccatgggcga gggcggcccg
     9001 gcgtcgctgt tcttcgacga cgtacgcgta ccgcaccgca acatcctcgg cgaggagggc
     9061 caggggttcg cgctggccat gcagtggatc ggcaagggcc gctacaccat cccctcacac
     9121 gccgtcggca tcgccgaacg ggcactgcgg atggccatcg atcacgccaa cacccgggag
     9181 accttcggca ccaagatcgg caccaaccag gccatccagt ggatgatcgc cgactcggag
     9241 accgagctgg aagccgcccg ctggctcatc ctgcgggccg cctggacggt cgacgccgga
     9301 atggaccccc ggcacgcctc ctccatggcg aagctctacg gcgccggcat ggtcaaccgg
     9361 gtggtcgacc gggtcatgca gatccacggc gggatgggct acacccgcga actgccgatc
     9421 gaacgctggt accggcaggt gcggctgtac cggatcttcg agggcaccga cgagatgcaa
     9481 cgactgatca tctcccgcga cctgctgcgc ggctacacga aactcggagg acacctggga
     9541 tgaggacctt cgccagcatc gacgagttgg ccggcgcggt cggcgagccg ctcggccccg
     9601 gcccgtggtt cccggtcgac aaacgtcggg tcgagctgtt cgccgacgcc accgacgacc
     9661 accagtggat ccacctcgac caggaacggg cggcagccgg accgtacggc ggcaccatcg
     9721 cccacggcta cctgacgctc tccctgatac cggccctggt cggccagctg taccgggtcg
     9781 acggggtgcg gatgggcatc aactacggcc tcaaccgggt ccgctttccc gcaccggtac
     9841 gcgtcggcag cgcggtacgg gtcgtcgcca ccatcgacca ggtcaccccg ttcgacggcg
     9901 gggcgcagct ggtcgccacg gtgacggtgc acaacgacgg cggtgacaag ccggtctgcg
     9961 tggccgagac ggtgagccgg ctgtacaccg acccgccccg atgaccacgc tctccccggc
    10021 gaccgtgctg gccggctccg cccgccggca cgccgacacc gtcgccgtcg tcgacggacg
    10081 ggtccgcgtc acgtacgccg aactgtggtg ggaggcccgc tgctacggcg ccgggctacg
    10141 tgccgcaggg gtacgcgccg gcgacacggt ggccctgctc gcaccgaacg tggtcgactt
    10201 tccccgggtc tactacgccg ccctcgccgc cggtgcgcac gccgtgccga tcggcgcgcc
    10261 gaccagcccg cagacggttc acctgctgcg cggcgcgcga ctgctcgtct gccacacctc
    10321 acaactggcc gccgggcagt gggtcagcgc ccgggccggc gtaccgctgg tcaccgtcgg
    10381 accgacccgc ggcccgtccg gcgtaccccg gctggaagac ctcagcgacc ccgcacccgg
    10441 cggcgccgct gcggacccgg acaccgacga cgacccggcc ggccggaccg cgaccgaccc
    10501 ggacgacggc gacgtggtgc tcagctgcct gccactgggt ggccgcttcg gccaggacgt
    10561 cgcactgacc ggcaccttcg ccgccggggc gaccctggtg ctgctgagcc gattcaccgg
    10621 cccggcggca ctggagctca tgctccgcga ggaggtcacc gtcttccacg gcacctcggc
    10681 gatgtacgcg gccctgctcg acgcggcgcg gggcaggcag accctgcccc ggctgcgacg
    10741 ctgcgtcagc aggacccccc tgccaccggc cctgggacag cccttcacga ccgccttcgc
    10801 caccgtcgtc accgtggccg aggagaagtc ccgatacggc ggtggccgac ggcagcgctg
    10861 gcgctgccga caccggcagg ggaaaggacg ctgacgacga catcagtcgg ctggtggggg
    10921 accggtctcc agcagacgtc cctcggcgag ccgcagccag cggctgacct tgatctccgc
    10981 gaggaaccgc tcgtcgtggc ttaccaccaa cagcgcaccc cgataggcgt tgagcgcact
    11041 ctccaactga ccgacgctga ccaggtcgag attgttggtc ggctcgtcga gcagcaggag
    11101 ctgcggtgcc ggctccgcgc ccaggacaca ggccagagtg gcacgcagcc gctcgccacc
    11161 ggagagcacc ccgaccggca gctgcgctcg ggcgccccgg aacaggaaac gggcgagcag
    11221 gtgcatccgc cgcgcctccg gcgcctgcgg cgcgaacacc gccaggttct ccgccaccgt
    11281 acgctccgga tccagcaggt ccagccgctg cgacaggtac gcgatccggc cgtccgcccg
    11341 tctgatctgg ccaccctcgg gctccagagt gccggtgacc aggcgtagca acgtggactt
    11401 gccggcaccg ttggcaccga gcaacgcgat ccgctccggg ccccggatcg tcaggtcgac
    11461 gccgtcgtcg gcgaagaccg gccgcccacc gtagcggacc tgcatccgtt cagcggccag
    11521 caacgtgcgg ccggccggca cctgggtgcc gggcagttcc aaggagagct tctgctcgtt
    11581 gcgcagcgcc tgccctgcct cgtcgagccg ggccttcgcc tcgctgaccc gcgcggaatg
    11641 cagctcgtcc gccctgcccg ccgactcctg ggcgttgcgt ttcagcgtgc cggcgaagat
    11701 cttcggcagg cccgcgttct tgaggttgcg cgaggcgttg ccggcccgcc gcgccgcccg
    11761 ctcgcgggcc tcctgcaact cccgcttctc ccgcttgagt tcctgctcgg cgttgcggac
    11821 gttcttctcc gccacctcct gcgcggcgcg caccgctgcc tcgtacgcgg tgaagttgcc
    11881 gccgtagaac cgaagatcgc cgcggtccag ttcggcgatc cggtccatcc ggtccagcag
    11941 cgcccggtcg tggctgacca gcagcagaca gccggtccac tgctccagca cctcggcgag
    12001 cttgtgccgg gcctcgatgt cgagattgtt cgtcggctcg tccaacagca gcacgtcggg
    12061 ccgcttcaac aactgcgcgg ccagaccgag ggagacgacc tgcccgccgc tgagcgtgtc
    12121 cagacgccga tcgaaggcca ggtcaccgag gccgagccgg tccaactgcg cacgggtccg
    12181 ctcctcgatg tcccagtcgt tgccgatcgt ggtgaagtgc tcctcgtcgg cgtccccgga
    12241 ctcgatggca tgcagtgccc cgatcagcgg agcgatctcc agcacctcgg ccacggtgcg
    12301 gtcaccgacc agcggcaggg tctgcgggag atagcccagt accccctggg tcgagacgga
    12361 cccggcggtg ggtcggtact cgccggcgag cagccgcagc agggtgctct tgccggcacc
    12421 gttcggcgcg accaacccgg tacggccggc accgatcgtg aaggacaggt cctggaagac
    12481 cggggtgtca tccggccagg aaaagctcag gttcgagcag acgacgaaag aatcggacat
    12541 cgggacagaa cctcggatgt gagggcaggc ggacctcagc cgcccgacag gggggacacg
    12601 gtctggaaga aacgacaacc gtccacggca ccggcactca cgggcgcggg ccggacggcc
    12661 gatcacatgt ccggtctcac ccggagatgt cgtcgtctcc ctgcatgtct cgtctccctg
    12721 attcgctgac catccagggc cagatcctgc gtgaccacgg tagcaccggc ggcatccgat
    12781 tcgccggacg agccgcaggc cgagcccttc ctaggagtac caggaccagg ctgcccaccg
    12841 acgacgaacc taccgtggtc gacatggcga atccgagact aggtggacac cagcacgcgc
    12901 cgcgacaggt tttcggcacc cgacggggac gtcctgcacc acgcgggatc cgttctgcgc
    12961 cgccggtgac cggcgcggga agtccgtcgg caggacacac gtcccgccga cggactcggg
    13021 tggccgaagc ctatggtttg cgggcgagga gcccgacgaa ggtgtgatag gtgtcggtct
    13081 gctgtggagt tggcgtgcct gactccggac gccactcggc cagcggcacc agccccggct
    13141 ccagcaccgt cagcccatcg gcgaaggcga ggatctcctc gtcggtgcgc caacggccgg
    13201 tgcccagcga ctcgttgaag acccgttcga cctcgcgcgc cttgcgggag ccctccggat
    13261 cacgctcacc cgggtcccgg aagtgggaaa tcgccacgta gctgccggac ggcagcgcgt
    13321 cgatcaactc ggctgccaac gctcggggct gctcgtcgtc gccgacgtgg tgcaggatcg
    13381 cgaaaagcaa caacccgatc ggccggtcga aatcgaggaa ccgacgtacc tccggattgt
    13441 tgagaatctc ctgcggtgcc cggacatccg cctggatcac cgtcgccgtg ccctcctcgg
    13501 cgagcagggc ccgcccgtgc gccagaacga tcgggtcatt gtccacatac accacccggg
    13561 ccttcgggtt gtgctcggtg gcgacctcgt gcacgttgcc ctgggtgggc agccctgatc
    13621 cgatgtcgag gaactggtcg atgccggcct cggtgacaag gaagcgaatc acccgacgca
    13681 gaaaggcccg gttcgcctgg ccggctgccg gcccgtccgg ggtgatccgc agggcgtgtt
    13741 cggcgacctt tcggtcgacc tcgaagttgt ccttgccgcc gagaaagaag tcgtagaccc
    13801 gggcgacgct gggaatgctg gtgtcgatgc cagggggtgc cgccttgtcg cgggtcacag
    13861 gcgtctccat tcaatgagga acaacgccgg gtgaagtctg cgggcggttc cggcgctgcg
    13921 gtgagtgtag ccatcgactg ggcggaattc tcaccctgcc tggtatcgct cccagcagac
    13981 gtggcctcag tcgaccggca gcagcgcgat cccctgcatc tcgatcagca ggtgcgggtg
    14041 cggcaactgg tgcaccgcca cggtggtacg cgtcggcccg gtctcgtcga agagttcggc
    14101 gtacacccgg ttgtagccgc cgaagtcgtt catgctgacc aggtacgtgg tcacctgcac
    14161 cagatcggac aggtccgcgc ccacctcgcg caggatgtcg cgcatgttct cgatcaccgc
    14221 gcgggtctgc acctcgatgt ccaacgaggt ggtacccagc gcgtccaccg tcgcaccggc
    14281 gatcgtgttg tcgggacggc ggctgctcgt accggagacg aaggcgaacc cgcccgcgac
    14341 cttgacgtgc gggaaccggc cacgcggcac ggccttgccg gcgacgaccc gagccccgct
    14401 catgccgagg cccgcagcga gacggtgccg agctgctcga cggtgacccg cacgtgcgcg
    14461 cccggcgtca ggggcaccgc ggcggtcgcc gcgccggcca gcagcaccca accgtcgcgc
    14521 agttccccgg cgaggcgggc cgcctcgggc agggcgcggc gcgggtcgcc gaggatcgcc
    14581 gcggtcgagc cgacctgcgc gacccgaccg tcgacctcca gcagcacgcc gaggttgtcc
    14641 acgttgtcgg gcaccggctg ccacggcccg acgacgaagc cggatgcgga ggtgttgtcg
    14701 gcgatcacct cggccagggt gaaccggaag tcccggtacc gggagtcgat gagctcgacg
    14761 gcgggggcga cggcggcgat cgcgccaccc tcgacgagga acgccacctc cggctcgacc
    14821 ttcggatgga tgtgtccgga caggtcgacg gtgccgccgt cacagatgtg catcgcgtcg
    14881 gtgagccgac cccagatcac ctcgtcgacg cccatctggg tcatcttcgc ccggctggtc
    14941 aggcccagct tcaccccgac caccgcctca ccacggccca cccggcgtgc caccagggcg
    15001 tcctgcacct ggtacgcggt ggccacgtcg aggccggcgt cggcaccgaa ctgggcgagc
    15061 gcggtccgcg tcacggcggc ctcgtccagc cgggcggcga tagtgtcgat cactgcgggt
    15121 ccttcccggc gtcccggacc aggtccagcg ccacgtcgac gatcatgtcc tcctggccgc
    15181 cgaccatctt gcggcgaccc aactccagca ggatggtgcg cacgtccacc ccgtaccgcc
    15241 cggcggcgct ctccgcgtgc cgcaggaacg acgagtagac cccggcgaaa ccgagcgaca
    15301 acgtctcccg gtccacccgc accggccggt cctgcaacgg acgcaccaga tcctcggcgg
    15361 cgtccatcag cgcgaacacg tcacaaccgt gcttccagcc gttcagctcg gccaccgcga
    15421 cgaagacctc cagcggcgcg ttgcccgccc cggcacccat cccggccagt gaggcgtcca
    15481 cccggcgcac cccgtgctcg accgcgacga ggctgttggc caccccgagt gacaggttgt
    15541 ggtgcgcgtg gatgccgatc tccgtcgtcg gatcgagcac ctgccggtac gcgtccgcgc
    15601 gctgcgccac gtccgccatg gtcagccggc caccggagtc ggtgacgtag acgcagtgcg
    15661 ccccgtacga ctccatcaac ttggcctgcg cggccagtcc ggccgggtcg aacatgtgcg
    15721 acatcatcag gaacccggac acgtccatgc cgttgtcccg cgcccaggag atgtgctgcg
    15781 cggagatgtc cgcctcggtg cagtgcgtgg cgatccgcac actcgtcacc ccgagggcct
    15841 tggccgcctt caggtcggcg atggtgccga taccgggcag cagcagggtg gtcagcttcg
    15901 cgttcgtcat cacctcggcc gccgccgcga tccactcggc gtcgcttgcc gcaccgtggc
    15961 cgtagttgac actcgacccg gccaacccgt caccgtgcgc cacctcgatc gcggccaccc
    16021 cggcggcgtc caacgccgca gcgatggtcc gcacctggtc cacggtgtag cggtgcccga
    16081 tggcgtgcat gccatcgcgc agcgtcacgt cctggatgta gagatcggtc acgacgagac
    16141 catccgttcg gccgtacgca gcgcggcgct tgtcatgatg tccaggttgc ccgcgtacgc
    16201 gggcaggtag tggccggcac cggagacctc caggaacacg gagacctgaa tgccgacgaa
    16261 gtgcccgccg agcgccggca cgtacgtgtc cacctcggtg aactgcacct gctgcttgag
    16321 ccggtagccg ggcacgtact gctgcaccgc cgccaccatc gcctccaccg acgccgcgat
    16381 cgcgtcgcgg tcggcgtccg gatcggggca caggcagtag accgtgtcgc gcatcagcag
    16441 cggtggctcc gccggattca gcacgatcac cgccttgccg cggcccgccc cgccgaccac
    16501 ctcgatggcc cgggcggtgg tctcggtgaa ctcgtcgatg ttggcgcggg tgcccggacc
    16561 ggccgaacgg gaggagatcg aggcgacgat ctcgccgtac gccaccggcg tgacccggcg
    16621 taccgcggcg acgatcggca cggtcgcctg cccgccgcag gtgaccatgt tgacgttgcg
    16681 ctcgcccagg tgggcgtcga ggttcaccgg cggcaccacg tacgggccga tggcggccgg
    16741 ggtcaggtcg acgacccggc ggccgtgggc gcgcagcacc gcgtcgttgt gccggtgcgc
    16801 gcccgcgctt gtggcgtcga agacgatccc gacgtcggcg aactccggca tcgcgacgag
    16861 cccgtcgaca cctgcggcgg tggtggccac accgagccga cgggcccggg ccagaccgtc
    16921 ggagtccggg tcgatgccga ccatcgccac catccgcagc gactccgaca gccgcaacac
    16981 cttgatcatc aggtcggtgc cgatgttgcc ggaaccgatc accgccacgc cggtgctcat
    17041 gacgcgccac ctttcgttct cgactgcggg gctcgcaaaa ccggctcact cctcgcgctc
    17101 acggagccac ctttcgttct cgactgcggg gctcgcaaga ccggctcact cctcgcgctc
    17161 acgagccacc tttcgagaag caggcccgga cgctgcccag gccggagata cgggcctcgt
    17221 acgccgcgcc cggagtcacc gccaccatcg ggccgagcgc gccggacaac acggtgtccc
    17281 cggcccgcag cggccgaccg ttcgcggcca gagtcccggc cagccaggcg acggcgtgca
    17341 acgggttgcc caggcacgcc gccccggccc cgacggagac gggctcgcca ccctgctcca
    17401 gcacggcacc gcagagccgc aggtcgacct cgcccagccg gcgcggactg gtgccgagca
    17461 cgtacctgcc gctggaggcg ttgtcggcca ccgtgtccac gatggagatg tcccagttcg
    17521 cgatccgcga gtcgacgatc tcgatggcgg gcagcaggtg atcggtggcc cgcaccacgt
    17581 cggcgacggt gacctggtcg tagggcaggt cgcggccgag gacgaaggcg acctccgcct
    17641 cgacgcgcgg ctgcaacagg gtccgcgggt cgatctcggc gccgtcgggg acggccatgt
    17701 cggcgaagag gacaccgaag tcgggttgga agaccccgaa cgcctcctgc accgcccgcg
    17761 aggtcaggcc caccttcgcc ccgaccagcc ggcgaccctc ggccagccag tcactgacct
    17821 gggcctgctg cacggcgtac gcggcggtca ggtcaccggc cggcagcagg tcgtcgcgca
    17881 acggctcaca ggccactccg ctggcgtacg cctggcgcag cgccgcggcc gcgcccttga
    17941 tgtcggcgct catccgaggt ccacgcagac gtttgtgagt tcggagtaga agtgcagcga
    18001 atgggtgccg ccctcgcgtc ccacgccgga cgccttcacc ccaccgaacg gggtgcgcag
    18061 atcccgcagg aaccacgtgt tcacccagac cagcccggcg tccagccgtg ccccggcccg
    18121 gtgcgcccga cccacgtcgc gggtccacac cgtggcggcc aggccgtact cgctgtcgtt
    18181 ggccagcgcg aacgcctcgt cctcgtcgtc gaacggcgcg atgtggcaga ccggaccgaa
    18241 gatctcctcc cgcatggtgc gggcgtgccg ccccaacccg gtcagaacgg tgggctgcac
    18301 gtacgagccg ctgtcgcggt cgtcgccgaa caccggcacg ccaccgccgg ccagcacggt
    18361 ggccccctcg gcgcgggcca gctcgtagtg gccgagcacc ttctcccggt gcttggccga
    18421 gatcagcggc atcgtcatcg tcgccggctc ggacggccaa ccgaacgcca gctcctcggc
    18481 ccgcttcgcc aaccgggccg cgaactcctc gaagaccggc cgctgcacgt agatccgttc
    18541 ggtgcacagg cagacctgac caccgttggt gaagctggac cgcaccgagc cttcgacggc
    18601 cgcgtccaga tcggcgtcgg cgaagaccag cccggcgttc ttgccgccca gctcgaacga
    18661 caccgccttc accccgtcgg ccgcggcacg catgatggcc gagccggtgg cggactcgcc
    18721 ggtgaaggtg atcgcgtcca cccccggatg gcgggtgagc gcctcacccg ccgagccggg
    18781 accgaagccg tgcaccaggt tgaacacccc gtcgggtacg ccggcggcgg ccatcacctc
    18841 ggccagcacg gtcgccgacg acggcgtctc ctcgctgggc ttgacgacca ccgcgttgcc
    18901 gcaggccagg gccggtgcca ccttccaggt cagcagcagc agcggcaggt tccacggcac
    18961 gatgatcgcc accacgccga ccggcttgcg gaccgcgtag ttcagcgccc gcccaccgct
    19021 cgcggtgacg gtggtgaacg actccgtcgg ggtggccgtg atgatgtcgg cgaacgtccg
    19081 gaagttcgcc gcaccgcgtg ggatgtccag ggtgcgggcc tgggccaccg acttgccggt
    19141 gtcggcgacc tcggcggcga cgaggtcgtc gaaacggcgt tccaactcgt cggcgacccg
    19201 gcgcagcacc gcggcccgct cgccctcgcc catggcaccc cacgggccgc gcagcgcggc
    19261 ccgtgcggcg gtcaccgcgg cgtccacggt ggcctggtcg gcctcggcga cgtgcagcag
    19321 cgtctcaccg gtcaccggcg acaccttggc gaacgaggtg ccgccggtga cgaactcacc
    19381 gccgacgtag ttcggtagca gcaggtcgcc gctgcggcgc ccgtcgatca ggccgctcgg
    19441 ccaacgggtg gtacgcccgg atgtcatggg cttggttccc tatcgttcgg tggtggagtc
    19501 agcgacgagc gccacgacgg ccgcgtcggc cgtcggctcg cccgtggccg cggctgccgc
    19561 ctcgtcggtg gcgatcagca cgacggtgcc gacgccgacg ttgagcgggt cgatcgcgac
    19621 caggtcgggc ccctcgctgc ggggccggac cagcaccagc cggcggccct gcaacgtggg
    19681 caggatcttg tccggccaga ccttggcgac gacctcaccg agaatcatca gccgtctccc
    19741 cgcaggcttg ccatgacctc gcggatgcgg gcggcctccg ggtcctccag cagcgccgcc
    19801 gtggtgggat gcggcttggg gtacacctgc gagctgcgca gctcgccgtg ctgccggatg
    19861 gcggcctcgc cggcggccac ggcctgccgg acggcggcga gggtgccctg cacggcggcg
    19921 gcaaggtaac cgctggtcac ccgctccacg gcgatgcagc gtacgtccgc agtcttgatc
    19981 atggcttcga tcccggcgga cagggccacc acgccccggg tctcgacgat gccgatggcg
    20041 atgtcagaag gcatgtgttg ttctccttac cgggtcagtt gccgacgagg cgagggtcga
    20101 cggcgagcgc cgacaccgcg tcacaggggc tggcgaagac gatggaacgc accttccggc
    20161 tcttggcctt ggcggtttcc tcgccgatgt cgacggcctc ctcgacggtg gccaggtcgc
    20221 cgcgcagggc gacggcgacg atgccgccgc cgaggcgcac gacgcgggtc acctcgacct
    20281 cggtggcctt caccatcgcg tcgaccgcgt cgaagatggc ggtgtagccc tcggcctcga
    20341 cgaagccggc agccatgttc cgcatgggtt ctccttttcc gatgttcagg gcaggttcca
    20401 ggacaggacg gcaccgccgg tgccccagag cggtccgtat gcgtgcagct gcgccggacc
    20461 ggccgtcgct ccggcgccgg cggcgaacgc cagcgcgcgg aactggctgt cggcctgcgc
    20521 ctgccgggcg aagtcctcgc ggatcttcaa cacctcgtcg accttgccgg cggtcagcag
    20581 gtccagcacc cgccggttcc agcggtcgtg cccggggtcg ctgacgtgat cgtcgtgcgg
    20641 ctcgatccac tgctggatca ggccggacga catgccggtg accacgacga cggcggcacg
    20701 gacgccggcc tcgcgggccg cggcggcacc ggccgcaccg acgtcggcga gggtctgcgc
    20761 gtcggcgtac aggttgcagg acacctgcgc ccagcgcagc tcgcggtccg ggtcgagcag
    20821 cgccgaggtg acgatggtgc cggtgtcgat cggaaagccg tcgtagcggg tacgccgggc
    20881 ctgcatgccg gccttgttca cgtgatcggt ccaccgctcg gtgaacggca cgtcgaagcg
    20941 caggtcgtag cggagctcgc cgtagtcgta ggcgtaccag ttctcgtcga cgtgctcgcc
    21001 gcgcgggttc gggtcgcact ggaactggtg gcccaggacg gtgaaccact gggtggacag
    21061 cagcagcacc acgtcgggct tgaggcgacg caaccgatcg cccacctccc gggcggcggc
    21121 agccaggtcg gcccagcact gcgcgggctt ctcggccagc aggtgcggca tgccgggcag
    21181 cagcgccccg gcgacgatgc cggtgtcagc cacggtgtcc tccttcgggc gtccactcga
    21241 cgaccgcgtt gccggtgccg atgatcgttc cgtagcccat gacgtcgccg ggcacctgcg
    21301 gccagcccat cgcggccaac atccaggtca ggctgcccgc cttggtctcc gacgcggtcg
    21361 cctcgatgtg ctcggtgatc agctcgcgca gcggcgcggt cggcccccgg cggatcgcct
    21421 ccagcagctt catgtcccag cggtactggt ggttgttgta cgggtgctcg cgttccatgt
    21481 cctccggcag ctccggctcc tcgtgccagt gcaggtggga cagggagttg gaggccagca
    21541 gcacggcccg gcggccggtc cgctcgacgg cccgtcgggt cgcctcgccc agcacctcca
    21601 tctcctccag cgacgcctcg gagtagaagt acgggttgtt gtttgccgac aacgacacca
    21661 ccgggatgtc ccaggccggg ttgaccaggt gcaacgcgcc gatggtggcg tagtccaccc
    21721 gcacccgggg gtcgtgcagc ttgcgggtga ccaggcccag gtcggtggcc tcgtcggcga
    21781 tggcctcgcc cagctccaca tcggtacgga agtcgtagga gtaccggaac aggtgcggga
    21841 agatcggctc gacggagaca ccgcgcgggt tgggcacgca gttgacgtgg tgaccgacca
    21901 tcgtgatcca gtgcggagcg tgcacgatca gcacatcggg gcggtgcacc tcgcggatgc
    21961 gcttgcgcag ccgctcgtac gcccagcgca gcacctccca gccgccggtg gaccgcggct
    22021 cgttctgcgg cgggttctcc gcgtagatca ggtgcggcgg gtgcgggctc agcaccccgg
    22081 cgacgatgcc ggcgcgggcg ggcgtcggct ccgccgaagg tcgttcggtg gtgtcgtagc
    22141 ggcgggcacc gcccgaacgg gcgggtgcca cgggcacgcg gaagactctg ctcatgccgg
    22201 tccctccccg gtcgtgcccc ggtcggccag cacccgcacg aacgtgcgct cgtcgggttc
    22261 ggcgccgagg atctgcagcc cgtcgtcgtc gagggccagt tggtcgtcgg tcaggtccgg
    22321 gtcgtgccgg acccaggccc gcaggggcgc ggggtgcggg ccgtggatct ccacgagggc
    22381 gccgtcggcc aggccggtgc ccggacccac gtaggcgagc cgtcgccggc cacgctcccc
    22441 ggtgtacggc tgccggtcgg tggtgccgac ccgcagccag gtgcgccggc ggcgcagttc
    22501 ctgccgggct gctgcggtcg cggcggcgtc gacccggccg tcggcgtcga accgcaggcc
    22561 gtagcggtgc tgcgcgtcgt cggcgtccag gtagccctgc gtcacgtcgt cggcgacggc
    22621 ggcgggttca cgctcgagcg gatcgcccca gccgccgcca cctgcggact ccatgacgag
    22681 cacgtcgccg ctgcgcatcg cgaagccggc gaccttgccg ggggtgtcga agtcgacccg
    22741 ttcgccgtcg gcgcggcgca cgaacgtcac ggtgggggca ccggggccac cacggtgcag
    22801 accgtacggc ggcacggtgg tgcggtcggt ctgcaccgag tacgccccgt tgctggcgag
    22861 cagccgggtt tcgcgtcggc tgcccagccc gccccggcgt gccccgtcgc cgcatgagcc
    22921 gagtcgcagc tcggaggcgt cgacgacgat cgggatctcc gtctccagcc gttcgacgga
    22981 ctggatggtg gagatgtcgc cgaggtcgac ggggttcatc gcgctcggac cgtcggattc
    23041 gaggaagccg ccgttgccac ctgcggggta gtcgtagtac aggtaggacc ggccggtgcg
    23101 ttggtccacg ccgccgatga ggttctggaa ggtggttccg aattggtcgg ctgcgatgag
    23161 gtcgggcgcg acctgactca gcgtggccat gaccgcggag atgacccgct tgcgtacctc
    23221 gctgtgcgcg ttggcgggcg cggggtaggc gacgtgcacg acggtgcccg gctcggtgtg
    23281 cacccgcagc ggccggaagg cgccgtggtt gaccaggccg ccggggtcca gcgcgctctt
    23341 gacggcgatg aagacgccgg cgacggtcat cgcccgcgag gagttgacca cggcggcgac
    23401 ctgcgtggac gagccccgga agtcggcgtc gatctcgtcg ccgtcgatgg tgagcacgca
    23461 gcgcaccagc gcggggtcgt accgcccgtc ggtgtagagg tcgaggtagt cctcgtagcg
    23521 gtagacaccg tcgggcagtt gccggatgcg gtcgcgcagc cgctgctcgg tgcggtccat
    23581 gttggcggcc acgctgtcga gcagcagtgg cgcgccgtag cggccgacga gttcgcgcag
    23641 tcgccgctcg gcggtgaagc aggcggcgat gcagctctcc aggtcaccgc ggcgctcgtc
    23701 ggccatccgc acgttggcga agaggatggc gtacgcggcg gcgttggggc ggccctgctc
    23761 gatcagcttg atcggcggga tgcgcaaccc ctcctgaagg atctcggtgg cctgcccgga
    23821 gacgctgccg ggagtcatcc cgccgatgtc ggcccagtgc atgcgcacgc aggggaagag
    23881 gaacaactcg ccgtcgacga agaccggggt gatcagtgtg acgtcgttga ggtgactgcc
    23941 gccccggtac ggatcgttga cgatgtacag gtcgccgggg cgcatctcgt cggcgaagtc
    24001 ggcgaagatc tcggcgacgg aagccggcat ggcgatgacg tgccctggca tgtcccggcc
    24061 ctgggccacc atctgaccct gcgggtcgaa caacgcgcag gagaagtcct gcgcatcggc
    24121 gatgacgggg gagtgcgcgg tgcggaagat cgtctggcgc atctcgcgca cgatcgagat
    24181 gagaccttcg gtcacgatct cgaggtcgat cgggttcaac gtcttggtca tgcgacgcct
    24241 catgggttcc gactcgtgat gacgagtggt ttggctttga cctcacacgg accatgtggt
    24301 cccgtgcatg gaccataatg tggtccgtgg tttatattgt gaaacactag caaccgagaa
    24361 ggtgggaagc aagatgtcgc aggtcgcagg accgtcccca gctgcggagg gaccggccgc
    24421 ccgggaatcg ggcacccagg cgctcgaccg cgcgctcagc gtgctgctgg ccttccgcag
    24481 tggcggcgtc gaacgcaagg tcagcgacgt cagtcgcgag ctgggactgc acaagtcgac
    24541 ggccagccgg ttgttccggg cgctcgccga caccggcttc ctgcaacgca acgaggagac
    24601 cggcgcgtac cggctcgggg tcaccgtctt cgagttgggc gcctgcttcc tcgaagggct
    24661 cgacatgcac gccctggccc ggccactgct gcaccagctc gcccaggacg agggcgagtc
    24721 ggtcaacctg tccatccgcg acgagctgga tgccctgtcg atctacatcg agcgcggcac
    24781 ccgcaacgtg cagctcgtct cccgcctcgg ccggcgcatc ccgctgtggt gcagcgcagc
    24841 cggcaaggcg ctgctgctcg acctcgacga cgagcagatc cgcgccatgt tcgccgacac
    24901 ccagttcaca ccgctgaccc cgaacaccat caccgacctg gacaccttcg ccaagcggat
    24961 gcaccaggtc cgcgagcagg gatgggcgct caacgacgag gagagcgaag agggcctgcg
    25021 ggtcgtcgcc gcgccggtac gcgaccggct cggccaggtc accgccgcga tcagcatctc
    25081 cgggccgatc ttccgcctcg acgagacccg cgtcgccgaa ctggccgccg ccgccgtccg
    25141 cacggcgaac gagctgtcgc gtcagctggg tcatggcgtg ggtgcggtct ggggggactg
    25201 accggctcag aagtgttcct gcacggcgtc cgggtgcacc cgcacgtgca gcagggcggg
    25261 gccggtgacc ggcagcaccg cgtcgaacgc ggcgtcggca ctggcctcgt ccgtcaccgt
    25321 ccacgccggc acacccagcg cccgagccac cgcagcgagg tcacggtcgg ggaagcgggc
    25381 cagcgccgga tccaccccac gcggacgcag cttgcgcacc tccgccccgt acgccgagtc
    25441 gtccaggacg atcaacagca ccgccgcgcc cgtacgggcc agggtgtcca gctcaccgag
    25501 cccggtgaac agactgccgt caccctcgaa cgccaccacc ggccggtccg ggcggcccac
    25561 cgcggcaccc accgcgaacg gcagccccac gccgatgctg ccgaactccc acggggcgat
    25621 cagcgcccgg tccgtcgccg gtgaatccag caacaggttc ggccagccgc cgaagtgccc
    25681 cacccccacc accgtggtgc gttgtggcgg cagtctgcgg gcgcagaccc ggatgaacgc
    25741 cctcgggtcg atccggtccg ccgcctgcaa cggttgcagc ccggcgaacg cgtcggccgc
    25801 cgccacctcc cgcgccagct ccgccgaccg ccactgcggc cgtgggatca ccggtagcac
    25861 cgccgacacc gccgacaccg ccgaagcgac cgtctccgcg tcgcccacca ccggcacgtc
    25921 caccggccaa cggtcaccca acgccgccgg gtcgatgtcg acgcacacca cagtggcctg
    25981 gccgaacagc cggccgtggt ccgcggtcca ccggttgagc ccggcaccga acgccaccac
    26041 caggtccgcc tcacccaaaa cccgccgggc cagcggccgg gccagaccac ccgccacccc
    26101 cagacagtac ggatggtcgg cgaagagacc tc
//
